Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147901 | 0.87 | MTNR1A (0.39) | NPC1LMNAMTNR1AMTNR1BCACNA1H | |
| SCHEMBL4761358 | 0.86 | NPC1 (0.38) | KMT2ANPC1MEN1LMNAMAPT | |
| SCHEMBL3828808 | 0.81 | CYP1B1 (0.40) | LMNAMAPTNPSR1GSK3AGSK3B | |
| SCHEMBL1898034 | 0.81 | NPC1 (0.44) | KMT2ANPC1MEN1LMNAMAPT | |
| SCHEMBL13535835 | 0.79 | HPGD (0.38) | KMT2ANPC1MEN1LMNAMAPT | |
| SCHEMBL10148032 | 0.77 | MEN1 (0.36) | KMT2ANPC1MEN1LMNAMAPT | |
| SCHEMBL4761412 | 0.77 | MGLL (0.42) | LMNAMAPTNPSR1GSK3AGSK3B | |
| SCHEMBL20224593 | 0.76 | NPC1 (0.41) | KMT2ANPC1MEN1LMNAMAPT | |
| SCHEMBL20224596 | 0.76 | NPC1 (0.41) | KMT2ANPC1MEN1LMNAMAPT | |
| SCHEMBL20365061 | 0.76 | CYP1B1 (0.44) | LMNAMAPTNPSR1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106131-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090012241-A1 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| US-7432331-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |