Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148010 | 0.90 | CNR1 (0.38) | MEN1KMT2AOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL13535835 | 0.89 | HPGD (0.38) | MEN1KMT2AOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL12094077 | 0.81 | KDM4E (0.38) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL12622422 | 0.81 | HPGD (0.35) | MEN1KMT2AOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL4761710 | 0.80 | CYP2D6 (0.38) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL4761358 | 0.80 | NPC1 (0.38) | MEN1KMT2ASMN1; SMN2HPGDHTT | |
| SCHEMBL4761681 | 0.79 | CNR2 (0.38) | MEN1KMT2ASMN1; SMN2HPGDHTT | |
| SCHEMBL10148049 | 0.78 | DRD2 (0.36) | OPRM1OPRL1SMN1; SMN2HPGDHTT | |
| SCHEMBL10147902 | 0.77 | KMT2A (0.40) | MEN1KMT2ANPC1LMNAMAPT | |
| SCHEMBL14016308 | 0.77 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106131-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090012241-A1 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| US-7432331-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432330-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |