Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148049 | 0.92 | DRD2 (0.36) | DRD2POLBSMN1; SMN2HPGDHTT | |
| SCHEMBL4761730 | 0.87 | POLB (0.33) | DRD2POLBSMN1; SMN2HPGDHTT | |
| SCHEMBL10148010 | 0.77 | CNR1 (0.38) | SMN1; SMN2HPGDHTTCNR1CNR2 | |
| SCHEMBL10148045 | 0.74 | POLB (0.34) | DRD2POLBSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL16062579 | 0.72 | CNR1 (0.39) | POLBSMN1; SMN2CNR1CNR2TDP1 | |
| SCHEMBL20752871 | 0.72 | SMN1; SMN2 (0.44) | DRD2POLBSMN1; SMN2HPGDHTT | |
| SCHEMBL20752666 | 0.72 | SMN1; SMN2 (0.44) | DRD2POLBSMN1; SMN2HPGDHTT | |
| SCHEMBL16784580 | 0.72 | HPGD (0.42) | DRD2POLBSMN1; SMN2HPGDHTT | |
| SCHEMBL14819092 | 0.71 | SMN1; SMN2 (0.43) | DRD2POLBSMN1; SMN2HPGDHTT | |
| SCHEMBL16784578 | 0.71 | SMN1; SMN2 (0.43) | DRD2POLBSMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106131-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090012241-A1 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| US-7432331-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432330-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |