Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148036 | 0.92 | DRD2 (0.36) | DRD2POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL4761730 | 0.81 | POLB (0.33) | DRD2POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL10148032 | 0.78 | MEN1 (0.36) | POLBHPGDHTTSMN1; SMN2NPSR1 | |
| SCHEMBL12094077 | 0.73 | KDM4E (0.38) | POLBHPGDSMN1; SMN2 | |
| SCHEMBL4761710 | 0.72 | CYP2D6 (0.38) | POLBHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL10148045 | 0.72 | POLB (0.34) | DRD2POLBSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL20752871 | 0.70 | SMN1; SMN2 (0.44) | DRD2POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL20752666 | 0.70 | SMN1; SMN2 (0.44) | DRD2POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL16784580 | 0.70 | HPGD (0.42) | DRD2POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL14016253 | 0.69 | NPC1 (0.33) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106131-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090012241-A1 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| US-7432330-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432331-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |