Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3464720 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EPOLBSMN1; SMN2PLAU | |
| SCHEMBL1668412 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBSMN1; SMN2PLAU | |
| SCHEMBL16404975 | 0.74 | AGBL2 (0.43) | ALDH1A1POLQKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL3643010 | 0.74 | ALDH1A1 (0.43) | ALDH1A1POLQKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL8408164 | 0.74 | PIK3CD (0.50) | ALDH1A1KDM4EPOLBSMN1; SMN2PLAU | |
| SCHEMBL27229540 | 0.74 | ALDH1A1 (0.42) | ALDH1A1POLQKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL25299377 | 0.70 | ALDH1A1 (0.60) | ALDH1A1POLBSMN1; SMN2HTTMAPT | |
| SCHEMBL30517122 | 0.70 | ALDH1A1 (0.60) | ALDH1A1POLBSMN1; SMN2HTTMAPT | |
| SCHEMBL15862919 | 0.70 | KMT2A (0.49) | ALDH1A1KDM4ESMN1; SMN2PLAUAGBL2 | |
| SCHEMBL1665443 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389546-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120015979-A1 | Compounds for Modulating TRPV3 Function | Hydra Biosciences, Inc, (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015979-A1 | Compounds for Modulating TRPV3 Function | TRPV3, TRPV1, TRPV4 | ALDH1A1 3074/4885POLQ 4852/4885KDM4E 3811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.