Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148420 | 1.00 | KMT2A (0.59) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL7401587 | 0.87 | KMT2A (0.65) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL6286653 | 0.86 | KMT2A (0.63) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| Benzyl Benzoate SCHEMBL3824242 | 0.83 | KMT2A (0.68) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL10186403 | 0.82 | LMNA (0.56) | TDP1LMNAFFAR1HPGDLTB4R | |
| SCHEMBL10186125 | 0.82 | LMNA (0.56) | TDP1LMNAFFAR1HPGDLTB4R | |
| SCHEMBL28881004 | 0.82 | KMT2A (0.76) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL12391751 | 0.81 | LMNA (0.74) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL13845264 | 0.81 | KMT2A (0.56) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL15614364 | 0.81 | KMT2A (0.69) | KMT2ASLC6A2SLC6A3TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | KMT2A 441/4885SLC6A2 428/4885SLC6A3 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.