Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.54 |
| ▸ | STS | P08842 | 5/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186125 | 1.00 | LMNA (0.56) | LMNATSHRCYP1A2CYP2C19ESR1 | |
| Isopropylbenzene SCHEMBL28857702 | 0.83 | LMNA (0.63) | LMNATSHRCYP1A2CYP2C19ESR1 | |
| SCHEMBL10148420 | 0.82 | KMT2A (0.59) | LMNASMN1; SMN2LTB4RLTB4R2FFAR1 | |
| SCHEMBL10148422 | 0.82 | KMT2A (0.59) | LMNASMN1; SMN2LTB4RLTB4R2FFAR1 | |
| SCHEMBL28978386 | 0.81 | LMNA (0.79) | LMNATSHRCYP1A2CYP2C19ESR1 | |
| SCHEMBL97514 | 0.81 | LMNA (0.79) | LMNATSHRCYP1A2CYP2C19ESR1 | |
| SCHEMBL1869078 | 0.81 | LMNA (0.79) | LMNATSHRCYP1A2CYP2C19ESR1 | |
| Butylparaben SCHEMBL5189352 | 0.81 | TSHR (0.68) | LMNATSHRCYP1A2CYP2C19ESR1 | |
| Hydrogen Peroxide SCHEMBL28645617 | 0.81 | ESR1 (0.82) | LMNATSHRCYP1A2CYP2C19ESR1 | |
| SCHEMBL29523345 | 0.80 | LTB4R (0.57) | TSHRSMN1; SMN2LTB4RLTB4R2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | LMNA 2889/4885TSHR 4189/4885CYP1A2 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.