Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148426 | 0.90 | POLB (0.49) | POLBNPC1RAB9AMAOAMAOB | |
| SCHEMBL10184995 | 0.85 | LMNA (0.46) | POLBNPC1RAB9AMAOAMAOB | |
| SCHEMBL17053655 | 0.81 | HRH3 (0.55) | NPC1RAB9AHRH3PARP10KDM4E | |
| SCHEMBL20325744 | 0.81 | HRH3 (0.53) | NPC1RAB9AMAOAMAOBHRH3 | |
| SCHEMBL241349 | 0.80 | POLB (0.57) | POLBTSHRMAPTHPGDALDH1A1 | |
| SCHEMBL664676 | 0.80 | POLB (0.57) | POLBTSHRMAPTHPGDALDH1A1 | |
| SCHEMBL10147939 | 0.80 | POLB (0.57) | POLBTSHRMAPTHPGDALDH1A1 | |
| SCHEMBL10148163 | 0.80 | ALDH1A1 (0.48) | POLBMAOAMAOBMAPTHPGD | |
| SCHEMBL10148311 | 0.79 | NPC1 (0.46) | POLBNPC1MAOAMAOBHRH3 | |
| SCHEMBL10148171 | 0.79 | ALDH1A1 (0.45) | POLBNPC1RAB9AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | POLB 3114/4885NPC1 201/4885RAB9A 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.