Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148461 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNARAB9AMAPTHPGD | |
| SCHEMBL14984454 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNARAB9AMAPTHPGD | |
| SCHEMBL10148457 | 0.89 | ALDH1A1 (0.51) | LMNAEPHX2ALDH1A1 | |
| SCHEMBL10148464 | 0.89 | ALDH1A1 (0.51) | LMNAEPHX2ALDH1A1 | |
| SCHEMBL601885 | 0.81 | PARP10 (0.45) | SMN1; SMN2RAB9APARP10KMT2ANPC1 | |
| SCHEMBL601886 | 0.81 | PARP10 (0.45) | SMN1; SMN2RAB9APARP10KMT2ANPC1 | |
| SCHEMBL17873483 | 0.81 | LMNA (0.61) | SMN1; SMN2LMNARAB9AMAPTHPGD | |
| SCHEMBL10188555 | 0.80 | LMNA (0.53) | SMN1; SMN2LMNARAB9AMAPTHPGD | |
| SCHEMBL10186405 | 0.80 | LMNA (0.51) | SMN1; SMN2LMNARAB9AMAPTHPGD | |
| SCHEMBL10186127 | 0.80 | LMNA (0.51) | SMN1; SMN2LMNARAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | SMN1; SMN2 4464/4885LMNA 2889/4885RAB9A 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.