Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123594 | 0.82 | CYP2A6 (0.38) | MAPTTDP1KDM4EALDH1A1HPGD | |
| SCHEMBL343188 | 0.76 | CSNK2A1 (0.34) | — | |
| SCHEMBL343474 | 0.70 | CA12 (0.44) | MAPTTDP1KDM4EALDH1A1HPGD | |
| SCHEMBL10123575 | 0.70 | MAOA (0.35) | KDM4EALDH1A1HPGD | |
| SCHEMBL344208 | 0.69 | KDM4E (0.43) | MAPTTDP1KDM4EALDH1A1HPGD | |
| SCHEMBL4697051 | 0.69 | ALDH1A1 (0.51) | KDM4EALDH1A1 | |
| SCHEMBL10123651 | 0.68 | CDC7 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL10123635 | 0.67 | GABRA1 (0.37) | — | |
| SCHEMBL10123639 | 0.66 | KIF11 (0.35) | MAPTTDP1KDM4EALDH1A1HPGD | |
| SCHEMBL13601191 | 0.66 | MRGPRX4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415771-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |