Sugi Predict

Sugi Predict / Compounds / SCHEMBL10149209

SCHEMBL10149209

SCHEMBL10149209

CCc1cc(C)c(O)c(Br)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 2/20 0.43
▸ PTGS2 P35354 2/20 0.43
▸ ALOX5 P09917 1/20 0.43
▸ SHBG P04278 1/20 0.39
▸ ESR1 P03372 3/20 0.39
▸ ESR2 Q92731 2/20 0.39
▸ HMGB1 P09429 1/20 0.37
▸ CXCL12 P48061 1/20 0.37
▸ PTPN1 P18031 1/20 0.37
▸ CYP3A4 P08684 2/20 0.37
▸ TSHR P16473 2/20 0.37
▸ TDP1 Q9NUW8 2/20 0.37
▸ CA1 P00915 2/20 0.37
▸ CA2 P00918 2/20 0.37
▸ GAA P10253 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ PKM P14618 1/20 0.36
▸ HSPA5 P11021 1/20 0.36
▸ TRPA1 O75762 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1250655 0.86 TSHR (0.50) PTGS2ALOX5ESR1PTPN1CYP3A4
SCHEMBL69899 0.84 SHBG (0.55) PTGS1PTGS2SHBGESR1ESR2
SCHEMBL31169642 0.84 SHBG (0.55) PTGS1PTGS2SHBGESR1ESR2
SCHEMBL1023068 0.84 PTGS1 (0.55) PTGS1PTGS2ALOX5SHBGESR1
SCHEMBL27613126 0.83 PTGS2 (0.43) PTGS1PTGS2SHBGESR1ESR2
SCHEMBL11072308 0.81 PTGS2 (0.44) PTGS1PTGS2SHBGHMGB1CXCL12
Water SCHEMBL31169652 0.81 SHBG (0.52) PTGS1PTGS2SHBGESR1ESR2
SCHEMBL5599293 0.81 PTGS2 (0.44) PTGS1PTGS2SHBGESR1ESR2
SCHEMBL8433981 0.80 TRPA1 (0.46) ESR1PTPN1CYP3A4TSHRTDP1
SCHEMBL26113500 0.78 GABRA1 (0.39) PTGS1PTGS2SHBGHMGB1CXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118266072-A Liquid molding compounds, and reaction products thereof that become electroplatable when exposed to laser energy 汉高股份有限及两合公司 2024-06-28 — — CN disclosed
WO-2023091578-A1 LIQUID MOLD COMPOUNDS, REACTION PRODUCTS OF WHICH BECOME PLATABLE UPON EXPOSURE TO LASER ENERGY HENKEL AG & CO. KGAA (DE) 2023-05-25 — — WO disclosed
CN-112567509-A Liquid compression moulding or encapsulant compositions 汉高知识产权控股有限责任公司 2021-03-26 — — CN disclosed
EP-3494157-B1 STABILIZERS FOR BROMINATED POLYMERIC FLAME RETARDANTS BROMINE COMPOUNDS LTD (IL) 2021-03-03 — — EP disclosed
CN-107636039-B Curing agent for thermosetting epoxy resins and method for producing insulation systems for electronic engineering 亨斯迈先进材料许可(瑞士)有限公司 2020-11-24 — — CN disclosed
WO-2018025266-A1 STABILIZERS FOR BROMINATED POLYMERIC FLAME RETARDANTS BROMINE COMPOUNDS LTD. (IL) 2018-02-08 — — WO disclosed
US-9040706-B2 Pyrrolidine inhibitors of IAP GENENTECH, INC. (US) 2015-05-26 — — US disclosed
US-8980837-B2 Inhibitors of IAP GENENTECH, INC. (US) 2015-03-17 — — US disclosed
US-8907092-B2 Inhibitors of IAP GENENTECH, INC. (US) 2014-12-09 — — US disclosed
US-8835393-B2 Inhibitors of IAP GENENTECH, INC. (US) 2014-09-16 — — US disclosed
CN-101001887-B Multi-branched polymer and method for producing same NIPPON SODA CO.,LTD. (JP) 2012-02-08 — — CN disclosed
US-20120015974-A1 IMIDAZOPYRIDINE INHIBITORS OF IAP GENENTECH, INC. (US) 2012-01-19 — — US disclosed
CN-102298264-A Radiation-sensitive resin composition for forming cured film, method of manufacturing the same, cured film, method for forming the cured film and display device — 2011-12-28 — — CN disclosed
US-20110269696-A1 INHIBITORS OF IAPS GENENTECH INC. (US) 2011-11-03 — — US disclosed
US-20110218211-A1 AZAINDOLE INHIBITORS OF IAP GENENTECH, INC. (US) 2011-09-08 — — US disclosed
US-20110077265-A1 INHIBITORS OF IAP GENENTECH, INC. (US) 2011-03-31 — — US disclosed
CN-101593852-B Multibranched polymers and process for production thereof NIPPON SODA CO 2011-03-02 — — CN disclosed
US-20110046066-A1 INHIBITORS OF IAP GENENTECH, INC. (US) 2011-02-24 — — US disclosed
CN-101593852-A Multibranched polymers and manufacture method thereof NIPPON SODA CO (JP) 2009-12-02 — — CN disclosed
CN-101001887-A Multi-branched polymer and method for producing same NIPPON SODA CO (JP) 2007-07-18 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269696-A1 INHIBITORS OF IAPS XIAP, BIRC5, BIRC3 PTGS1 3006/4885PTGS2 3973/4885ALOX5 4782/4885
US-20110046066-A1 INHIBITORS OF IAP BIRC5, XIAP, BIRC3 PTGS1 2377/4885PTGS2 3613/4885ALOX5 4880/4885
US-20120015974-A1 IMIDAZOPYRIDINE INHIBITORS OF IAP BIRC5, XIAP, BIRC3 PTGS1 3172/4885PTGS2 3766/4885ALOX5 4858/4885
US-20110218211-A1 AZAINDOLE INHIBITORS OF IAP XIAP, BIRC5, API5 PTGS1 3554/4885PTGS2 3911/4885ALOX5 4635/4885
US-20110077265-A1 INHIBITORS OF IAP XIAP, BIRC5, BIRC2 PTGS1 2319/4885PTGS2 2359/4885ALOX5 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.