Diphenylmethane

Diphenylmethane

SCHEMBL1014928

N=C=O.N=C=O.OCCO.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.55
TDP1 Q9NUW8 1/20 0.46
PLA2G10 O15496 1/20 0.45
PLA2G2A P14555 1/20 0.45
LMNA P02545 1/20 0.45
TSHR P16473 1/20 0.44
IDH1 O75874 1/20 0.42
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
BCL2 P10415 1/20 0.40
BCL2L1 Q07817 1/20 0.40
HNF4A P41235 1/20 0.40
PTPN1 P18031 1/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
SLC22A2 O15244 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
AKR1B1 P15121 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL27961286 1.00 CALM1 (0.55) CALM1TDP1PLA2G10PLA2G2ALMNA
Diphenylmethane SCHEMBL16760974 0.92 CALM1 (0.46) CALM1TDP1PLA2G10PLA2G2ALMNA
Diphenylmethane SCHEMBL29135359 0.91 CALM1 (0.50) CALM1TDP1PLA2G10PLA2G2ALMNA
Diphenylmethane SCHEMBL28457396 0.91 CALM1 (0.67) CALM1PLA2G10PLA2G2ALMNATSHR
Diphenylmethane SCHEMBL15415 0.91 CALM1 (0.67) CALM1PLA2G10PLA2G2ALMNATSHR
Diphenylmethane SCHEMBL9449990 0.91 CALM1 (0.67) CALM1PLA2G10PLA2G2ALMNATSHR
Diphenylmethane SCHEMBL15414 0.91 CALM1 (0.67) CALM1PLA2G10PLA2G2ALMNATSHR
Diphenylmethane SCHEMBL333766 0.91 CALM1 (0.67) CALM1PLA2G10PLA2G2ALMNATSHR
Diphenylmethane SCHEMBL465158 0.91 CALM1 (0.67) CALM1PLA2G10PLA2G2ALMNATSHR
Diphenylmethane SCHEMBL28763356 0.91 CALM1 (0.67) CALM1PLA2G10PLA2G2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111944492-A Preparation method of graphene nano composite phase change material with cold accumulation characteristic 哈尔滨商业大学 2020-11-17 CN claimed
CN-111944492-A Preparation method of graphene nano composite phase change material with cold accumulation characteristic 哈尔滨商业大学 2020-11-17 CN disclosed
WO-2015187632-A1 POLYMERIC FILMS COMPRISING ANTIMICROBIAL AGENTS AVERY DENNISON CORPORATION (US) 2015-12-10 WO disclosed
EP-2055327-B1 Antimicrobial lubricious coating COVIDIEN LP (US) 2013-12-11 EP disclosed
EP-2259765-B1 COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES USING AN INTERPOLYMER CHANEL PARFUMS BEAUTE (FR) 2012-08-15 EP disclosed
US-20110014150-A1 COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES CHANEL PARFUMS BEAUTE (FR) 2011-01-20 US disclosed
EP-2259765-A1 COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES USING AN INTERPOLYMER Chanel Parfums Beauté (FR) 2010-12-15 EP disclosed
US-7820734-B2 Antimicrobial lubricious coating TYCO HEALTHCARE GROUP LP (US) 2010-10-26 US disclosed
WO-2009124976-A1 COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES USING AN INTERPOLYMER CHANEL PARFUMS BEAUTE (FR) 2009-10-15 WO disclosed
EP-2055327-A1 Antimicrobial lubricious coating Tyco Healthcare Group LP (US) 2009-05-06 EP disclosed
EP-1299718-A1 RADIO-OPAQUE POLYMERIC COMPOSITIONS Hydromer, Inc. (US) 2003-04-09 EP disclosed
WO-2001085214-A1 RADIO-OPAQUE POLYMERIC COMPOSITIONS HYDROMER, INC. (US) 2001-11-15 WO disclosed
US-6054504-A Biostatic coatings for the reduction and prevention of bacterial adhesion HYDROMER, INC. (US) 2000-04-25 US disclosed
EP-0520160-A1 Process for antimicrobial treatment of polyurethane BOC HEALTH CARE, Inc. (US) 1992-12-30 EP disclosed
US-4875287-A Shaving articles lubricious when wet and compositions therefor HYDROMER, INC. (US) 1989-10-24 US disclosed
US-4769013-A Bio-effecting medical material and device HYDROMER, INC. (US) 1988-09-06 US disclosed
US-4642267-A Hydrophilic polymer blend HYDROMER, INC. (US) 1987-02-10 US disclosed
US-4576156-A Prophylactic device and method ORTHO PHARMACEUTICAL CORPORATION (US) 1986-03-18 US disclosed
US-4119094-A Coated substrate having a low coefficient of friction hydrophilic coating and a method of making the same BIOSEARCH MEDICAL PRODUCTS INC. (US) 1978-10-10 US disclosed
US-4100309-A Coated substrate having a low coefficient of friction hydrophilic coating and a method of making the same BIOSEARCH MEDICAL PRODUCTS, INC. (US) 1978-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014150-A1 COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES CUTA, SPOP, VCL CALM1 3942/4885TDP1 654/4885PLA2G10 564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.