SCHEMBL10149340

SCHEMBL10149340

CC(=O)Oc1cc(C)cc(CCc2cc(OC(C)=O)c(OC(C)=O)c(OC(C)=O)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.44
LMNA P02545 4/20 0.44
CYP4F2 P78329 2/20 0.43
CYP4A11 Q02928 2/20 0.43
ALOX5 P09917 2/20 0.43
TOP1 P11387 3/20 0.41
KDM4E B2RXH2 4/20 0.40
MAPT P10636 3/20 0.40
HTT P42858 2/20 0.40
ALDH1A1 P00352 2/20 0.40
GLA P06280 2/20 0.40
GAA P10253 2/20 0.40
CASP1 P29466 2/20 0.40
CASP7 P55210 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 2/20 0.40
MAPK1 P28482 1/20 0.40
BACE1 P56817 1/20 0.40
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL722695 0.90 CYP4F2 (0.47) ELANELMNACYP4F2CYP4A11ALOX5
SCHEMBL10149317 0.87 LMNA (0.52) ELANELMNACYP4F2CYP4A11ALOX5
SCHEMBL10149026 0.83 CCR5 (0.49) LMNACYP4F2CYP4A11ALOX5TOP1
SCHEMBL10182922 0.83 PTGS2 (0.49) LMNACYP4F2CYP4A11ALOX5TOP1
SCHEMBL16956859 0.82 LMNA (0.47) ELANELMNACYP4F2CYP4A11ALOX5
SCHEMBL13252213 0.81 LMNA (0.56) ELANELMNACYP4F2CYP4A11KDM4E
SCHEMBL10149336 0.80 LMNA (0.54) ELANELMNATOP1KDM4EMAPT
SCHEMBL10053943 0.79 TOP1 (0.53) ELANELMNATOP1KDM4EMAPT
SCHEMBL16546897 0.78 CYP4F2 (0.67) ELANELMNACYP4F2CYP4A11KDM4E
SCHEMBL16952285 0.78 LMNA (0.50) ELANELMNACYP4F2CYP4A11ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-10-06 US disclosed
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 ELANE 2013/4885LMNA 3479/4885CYP4F2 1710/4885
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 ELANE 2013/4885LMNA 3479/4885CYP4F2 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.