SCHEMBL10149026

SCHEMBL10149026

CC(=O)Oc1cc(CCc2ccc(C)cc2)cc(OC(C)=O)c1OC(C)=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 3/20 0.49
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
LMNA P02545 1/20 0.46
TOP1 P11387 3/20 0.45
CFD P00746 1/20 0.43
HTT P42858 1/20 0.43
PTGS1 P23219 1/20 0.42
PTGS2 P35354 2/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
AKT1 P31749 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
APEX1 P27695 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10182922 0.87 PTGS2 (0.49) CYP4F2CYP4A11LMNATOP1CFD
SCHEMBL717127 0.85 PTGS2 (0.55) CCR5CYP4F2CYP4A11TOP1CFD
SCHEMBL10149340 0.83 ELANE (0.44) CYP4F2CYP4A11LMNATOP1HTT
SCHEMBL13252304 0.82 HTT (0.46) CYP4F2CYP4A11LMNACFDHTT
SCHEMBL10148975 0.81 LMNA (0.60) CCR5CYP4F2CYP4A11LMNAKDM4E
SCHEMBL722695 0.81 CYP4F2 (0.47) CYP4F2CYP4A11LMNATOP1CFD
SCHEMBL3357654 0.78 THRB (0.46) CYP4F2CYP4A11LMNATOP1HTT
SCHEMBL10053943 0.77 TOP1 (0.53) LMNATOP1CFDHTTKDM4E
SCHEMBL178977 0.75 TRPV1 (0.57) CCR5CYP4F2CYP4A11CFDPTGS1
SCHEMBL10149023 0.74 TUBB4A (0.64) LMNATOP1HTTPTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-10-06 US disclosed
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 CCR5 585/4885CYP4F2 1710/4885CYP4A11 773/4885
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 CCR5 585/4885CYP4F2 1710/4885CYP4A11 773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.