Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 3/20 | 0.43 |
| ▸ | FNTB | P49356 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PRF1 | P14222 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 5/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10149522 | 0.86 | FNTA (0.39) | PPM1BFNTAFNTBIDO1KDM4E | |
| SCHEMBL343003 | 0.85 | PPM1B (0.40) | PPM1BFNTAFNTBIDO1PRF1 | |
| SCHEMBL27843160 | 0.74 | FNTA (0.58) | FNTAFNTBKDM4EKMT2AALDH1A1 | |
| SCHEMBL30456877 | 0.73 | PPM1B (0.71) | PPM1BIDO1KDM4EKMT2AGFER | |
| SCHEMBL2575452 | 0.73 | PPM1B (0.71) | PPM1BIDO1KDM4EKMT2AGFER | |
| SCHEMBL710309 | 0.73 | PPM1B (0.75) | PPM1BIDO1PRF1KDM4EKMT2A | |
| SCHEMBL29436316 | 0.73 | PPM1B (0.75) | PPM1BIDO1PRF1KDM4EKMT2A | |
| SCHEMBL23499274 | 0.71 | PPM1B (0.79) | PPM1BIDO1PRF1KDM4EKMT2A | |
| SCHEMBL29908977 | 0.71 | PPM1B (0.79) | PPM1BIDO1PRF1KDM4EKMT2A | |
| SCHEMBL30898594 | 0.70 | PPM1B (0.47) | PPM1BIDO1PRF1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415771-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |