Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10149523 | 0.86 | PPM1B (0.46) | FNTAFNTBRORCKDM4EKMT2A | |
| SCHEMBL343003 | 0.72 | PPM1B (0.40) | FNTAFNTBIDO1PPM1B | |
| SCHEMBL14392259 | 0.72 | ACMSD (0.59) | HNF4AACMSD | |
| SCHEMBL27843160 | 0.70 | FNTA (0.58) | FNTAFNTBKDM4EKMT2APTGS2 | |
| SCHEMBL14392421 | 0.70 | KMT2A (0.47) | KDM4EKMT2AGFERRXFP1PTGS2 | |
| SCHEMBL343467 | 0.66 | XDH (0.52) | RORCHNF4AACMSD | |
| SCHEMBL13985596 | 0.66 | ALDH1A1 (0.57) | KDM4EKMT2AGFERRXFP1PTGS2 | |
| SCHEMBL10149991 | 0.65 | XDH (0.54) | — | |
| SCHEMBL10123766 | 0.65 | RORC (0.46) | FNTAFNTBRORCKMT2AMEN1 | |
| SCHEMBL10148380 | 0.64 | KDM4E (0.47) | RORCKDM4EPTGS2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415771-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |