SCHEMBL10150702

SCHEMBL10150702

C/N=C(\C)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.56
MAPT P10636 4/20 0.56
L3MBTL1 Q9Y468 2/20 0.45
ALDH1A1 P00352 3/20 0.45
POLB P06746 1/20 0.45
WDR5 P61964 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HPGD P15428 2/20 0.42
MMP3 P08254 1/20 0.42
BCL2L1 Q07817 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3443698 0.85 LMNA (0.52) SMN1; SMN2MAPTL3MBTL1ALDH1A1POLB
SCHEMBL4547699 0.85 LMNA (0.52) SMN1; SMN2MAPTL3MBTL1ALDH1A1POLB
SCHEMBL3443700 0.85 LMNA (0.52) SMN1; SMN2MAPTL3MBTL1ALDH1A1POLB
SCHEMBL14274487 0.83 FURIN (0.48) SMN1; SMN2MAPTL3MBTL1POLBCYP1A2
SCHEMBL4316450 0.82 SMN1; SMN2 (0.56) SMN1; SMN2MAPTL3MBTL1ALDH1A1POLB
SCHEMBL3368876 0.82 SMN1; SMN2 (0.56) SMN1; SMN2MAPTL3MBTL1ALDH1A1POLB
SCHEMBL8720900 0.80 SMN1; SMN2 (0.54) SMN1; SMN2MAPTL3MBTL1ALDH1A1POLB
SCHEMBL4149626 0.80 SMN1; SMN2 (0.54) SMN1; SMN2MAPTL3MBTL1ALDH1A1POLB
SCHEMBL16437840 0.77 MAPT (0.56) SMN1; SMN2MAPTALDH1A1POLBNPC1
SCHEMBL22212833 0.77 FURIN (0.52) SMN1; SMN2MAPTALDH1A1POLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173350-B2 Oxime compound and resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-08 US disclosed
US-8173350-B2 Oxime compound and resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-08 US disclosed
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-01-28 US disclosed
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same CYC1, UQCRB, CBR1 SMN1; SMN2 1282/4885MAPT 3059/4885L3MBTL1 1811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.