Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4149626 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTWDR5ALDH1A1POLB | |
| SCHEMBL4041540 | 0.86 | LMNA (0.50) | SMN1; SMN2MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL3655561 | 0.86 | LMNA (0.50) | SMN1; SMN2MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL1005102 | 0.86 | LMNA (0.50) | SMN1; SMN2MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL10150702 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTWDR5ALDH1A1POLB | |
| SCHEMBL4316450 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTWDR5ALDH1A1POLB | |
| SCHEMBL3368876 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTWDR5ALDH1A1POLB | |
| SCHEMBL16437840 | 0.75 | MAPT (0.56) | SMN1; SMN2MAPTALDH1A1POLBNPC1 | |
| SCHEMBL15053148 | 0.75 | CYP19A1 (0.50) | SMN1; SMN2MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL2067685 | 0.75 | FURIN (0.44) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745154-B1 | MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND METHOD OF USING THIS SYSTEM | LIGNOZYM GMBH (DE) | 1998-09-16 | — | — | EP | claimed |