SCHEMBL10150825

SCHEMBL10150825

O=C(OCC1CCCCC1)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
MGLL Q99685 2/20 0.39
SLC1A3 P43003 3/20 0.39
SLC1A2 P43004 3/20 0.39
SLC1A1 P43005 3/20 0.39
MLYCD O95822 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
EPHX1 P07099 1/20 0.37
PARP15 Q460N3 1/20 0.37
PARP10 Q53GL7 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28052660 0.90 LMNA (0.37) LMNAMGLLSLC1A3SLC1A2SLC1A1
SCHEMBL685931 0.85 LMNA (0.47) LMNAMGLLSLC1A3SLC1A2SLC1A1
SCHEMBL686028 0.85 LMNA (0.47) LMNAMGLLSLC1A3SLC1A2SLC1A1
SCHEMBL12018633 0.85 LMNA (0.47) LMNAMGLLSLC1A3SLC1A2SLC1A1
SCHEMBL686209 0.85 LMNA (0.47) LMNAMGLLSLC1A3SLC1A2SLC1A1
SCHEMBL24142224 0.83 LMNA (0.46) LMNAMGLLSLC1A3SLC1A2SLC1A1
SCHEMBL685740 0.82 LMNA (0.44) LMNAMGLLSLC1A3SLC1A2SLC1A1
SCHEMBL13477592 0.82 LMNA (0.49) LMNAMGLLSLC1A3SLC1A2SLC1A1
SCHEMBL19335252 0.81 CNR2 (0.34) LMNA
SCHEMBL24142152 0.81 LMNA (0.43) LMNAMGLLSLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173350-B2 Oxime compound and resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-08 US disclosed
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same CYC1, UQCRB, CBR1 LMNA 1922/4885MGLL 3867/4885SLC1A3 3238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.