Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | HPGD | P15428 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798328 | 0.89 | ALDH1A1 (0.35) | MAPTALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL10132917 | 0.83 | TP53 (0.32) | MAPTMAPK1ALDH1A1HPGDTSHR | |
| SCHEMBL6742510 | 0.82 | MGLL (0.40) | MAPTMAPK1CYP3A4MGLL | |
| SCHEMBL6742282 | 0.79 | MAPT (0.33) | MAPTMAPK1TP53PPARGMGLL | |
| SCHEMBL13263802 | 0.79 | MAPT (0.33) | MAPTMAPK1TP53PPARGMGLL | |
| SCHEMBL6741984 | 0.77 | ALDH1A1 (0.35) | MAPTMAPK1ALDH1A1HPGDTSHR | |
| SCHEMBL13263935 | 0.77 | ALDH1A1 (0.35) | MAPTIRAK4ALDH1A1HPGDTSHR | |
| SCHEMBL6798063 | 0.77 | PKM (0.37) | MAPTALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL10165711 | 0.76 | CDK4 (0.30) | CDK4CCND1 | |
| SCHEMBL12203608 | 0.75 | ALDH1A1 (0.33) | MAPTALDH1A1HPGDTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183272-B2 | Indanyl compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-22 | — | — | US | disclosed |
| US-20110319359-A1 | INDANYL COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319359-A1 | INDANYL COMPOUNDS | RYR2, ORAI1, CASR | MAPT 1359/4885MAPK1 3096/4885ALDH1A3 3734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.