Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791394 | 0.90 | PKM (0.40) | PKMTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL12202398 | 0.82 | MGLL (0.40) | ALDH1A1CYP3A4KDM4ELMNACYP1A2 | |
| SCHEMBL12203684 | 0.82 | MGLL (0.40) | ALDH1A1CYP3A4KDM4ELMNACYP1A2 | |
| SCHEMBL17226933 | 0.80 | PKM (0.40) | PKMTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL6796223 | 0.80 | PKM (0.40) | PKMTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL6796536 | 0.78 | PKM (0.41) | PKMTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL17226978 | 0.78 | PKM (0.41) | PKMTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL6798328 | 0.77 | ALDH1A1 (0.35) | PKMTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL10151091 | 0.77 | MAPT (0.34) | PKMTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL10132915 | 0.77 | TP53 (0.38) | PKMTSHRALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183272-B2 | Indanyl compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-22 | — | — | US | disclosed |
| US-20110319359-A1 | INDANYL COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319359-A1 | INDANYL COMPOUNDS | RYR2, ORAI1, CASR | PKM 3505/4885TSHR 603/4885ALDH1A1 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.