SCHEMBL10153685

SCHEMBL10153685

c1ccc(C(c2ccccc2)(c2cn3c4ccccc4c4cccc2c43)c2cn3c4ccccc4c4cccc2c43)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GPR3 P46089 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153690 0.79 ALKBH5 (0.41) ALKBH5FTOKDM4EATML3MBTL1
SCHEMBL10313361 0.71 ALKBH5 (0.55) ALKBH5FTOKDM4EATML3MBTL1
SCHEMBL10153697 0.70 FGFR1 (0.37)
SCHEMBL10153718 0.68 ALKBH5 (0.39) ALKBH5FTOKDM4EATML3MBTL1
SCHEMBL10153680 0.67 EGFR (0.31)
SCHEMBL10153480 0.67 ALKBH5 (0.35) ALKBH5FTOKDM4EATML3MBTL1
SCHEMBL10153516 0.66 KDM4E (0.38) ALKBH5FTOKDM4EATML3MBTL1
SCHEMBL10313371 0.66 GPR3 (0.34) ALKBH5FTOGPR3
SCHEMBL10153711 0.66 ALKBH5 (0.41) ALKBH5FTOKDM4EATML3MBTL1
SCHEMBL10313382 0.65 SERPINE1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8421066-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2013-04-16 US disclosed
US-8421066-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2013-04-16 US disclosed
US-20120178928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-20120178928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-8174002-B2 Organic electroluminescence device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-8174002-B2 Organic electroluminescence device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-20100051928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed
US-20100051928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, CHRM1, LEF1 ALKBH5 1559/4885FTO 562/4885KDM4E 2229/4885
US-20120178928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, CHRM1, LEF1 ALKBH5 1559/4885FTO 562/4885KDM4E 2229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.