SCHEMBL10153690

SCHEMBL10153690

CC(C)(c1cn2c3ccccc3c3cccc1c32)c1cn2c3ccccc3c3cccc1c32

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.41
FTO Q9C0B1 1/20 0.41
GPR3 P46089 1/20 0.38
POLB P06746 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
KDM4E B2RXH2 2/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
HSP90AA1 P07900 1/20 0.30
IDO1 P14902 1/20 0.30
DUSP3 P51452 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153695 0.81 MAOA (0.37)
SCHEMBL10153685 0.79 ALKBH5 (0.35) ALKBH5FTOGPR3CYP1A2CYP2C19
SCHEMBL10153694 0.78 NLRP3 (0.37) ALKBH5FTOGPR3
SCHEMBL10313361 0.77 ALKBH5 (0.55) ALKBH5FTOGPR3POLBCYP1A2
SCHEMBL10313371 0.75 GPR3 (0.34) ALKBH5FTOGPR3POLBKIF11
SCHEMBL10313384 0.73 SMN1; SMN2 (0.36) ALKBH5FTOGPR3POLBCYP1A2
SCHEMBL10313382 0.73 SERPINE1 (0.33)
SCHEMBL10313386 0.72 MAPT (0.39) CYP1A2KDM4EMEN1ALDH1A1MAPT
SCHEMBL10153711 0.71 ALKBH5 (0.41) ALKBH5FTOGPR3POLBCYP1A2
SCHEMBL10153718 0.70 ALKBH5 (0.39) ALKBH5FTOGPR3POLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8421066-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2013-04-16 US disclosed
US-8421066-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2013-04-16 US disclosed
US-20120178928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-20120178928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-8174002-B2 Organic electroluminescence device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-8174002-B2 Organic electroluminescence device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-20100051928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed
US-20100051928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, CHRM1, LEF1 ALKBH5 1559/4885FTO 562/4885GPR3 2926/4885
US-20120178928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, CHRM1, LEF1 ALKBH5 1559/4885FTO 562/4885GPR3 2926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.