Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154478 | 0.79 | SLC6A4 (0.38) | KMT2AAURKAPARP1SLC6A4PDK2 | |
| SCHEMBL10154677 | 0.78 | KDM4E (0.41) | LRRK2CNR2KDM4EHTR2AHTR2C | |
| SCHEMBL10126647 | 0.76 | MAPK1 (0.36) | CNR2APP | |
| SCHEMBL3832735 | 0.74 | PDK2 (0.39) | KMT2AAURKAPARP1PDK2LRRK2 | |
| SCHEMBL21733021 | 0.73 | PDK2 (0.47) | AURKAPARP1PDK2AXLGPR84 | |
| SCHEMBL10126746 | 0.70 | MAPT (0.39) | KMT2AKDM4EMAPT | |
| SCHEMBL17857651 | 0.69 | HTR1A (0.40) | SLC6A4PDK2HTR2C | |
| SCHEMBL25858591 | 0.69 | CRBN (0.57) | — | |
| SCHEMBL29935587 | 0.68 | KMT2A (0.50) | KMT2AAURKAPARP1LRRK2ERN1 | |
| SCHEMBL1639313 | 0.68 | KMT2A (0.50) | KMT2AAURKAPARP1LRRK2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016117-A1 | INDAZOLEPROPIONIC ACID AMIDE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016117-A1 | INDAZOLEPROPIONIC ACID AMIDE COMPOUND | SCN9A, SCN1A, SCN1B | KMT2A 3609/4885AURKA 937/4885PARP1 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.