SCHEMBL10154503

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15034881	0.81	NPC1 (0.60)	NPC1RAB9AMAPTALDH1A1KMT2A
	SCHEMBL24303103	0.76	CYP2C19 (0.44)	MAPTKMT2ASMN1; SMN2CYP2C19GAA
	SCHEMBL20027158	0.76	RAB9A (1.00)	NPC1RAB9AMAPTALDH1A1KMT2A
	SCHEMBL24371155	0.74	CYP2C19 (0.45)	ALDH1A1SMN1; SMN2CYP2C19CYP1A2CYP3A4
	SCHEMBL31322256	0.73	CYP2C19 (0.42)	NPC1RAB9AALDH1A1KMT2AMEN1
	SCHEMBL3190736	0.73	CYP2C19 (0.48)	MAPTALDH1A1KMT2ASMN1; SMN2CYP2C19
	SCHEMBL10194217	0.72	RAB9A (0.53)	NPC1RAB9AMAPTALDH1A1KMT2A
	SCHEMBL11503706	0.71	RAB9A (0.70)	NPC1RAB9AMAPTALDH1A1KMT2A
	SCHEMBL6391556	0.71	ALOX12 (0.46)	NPC1RAB9AMAPTALDH1A1KMT2A
	SCHEMBL26328433	0.70	CYP2C19 (0.41)	ALDH1A1SMN1; SMN2CYP2C19CYP2D6L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.