Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24371155 | 0.79 | CYP2C19 (0.45) | CYP2C19SLC6A4SLC6A3SMN1; SMN2HIF1A | |
| SCHEMBL3190736 | 0.78 | CYP2C19 (0.48) | CYP2C19SLC6A4SLC6A3SMN1; SMN2HIF1A | |
| SCHEMBL24303103 | 0.78 | CYP2C19 (0.44) | CYP2C19SLC6A4SLC6A3SMN1; SMN2HIF1A | |
| SCHEMBL4166810 | 0.75 | TAAR1 (0.50) | CYP2C19SLC6A4SLC6A3SMN1; SMN2HIF1A | |
| SCHEMBL955632 | 0.75 | TAAR1 (0.50) | CYP2C19SLC6A4SLC6A3SMN1; SMN2HIF1A | |
| SCHEMBL10617967 | 0.74 | CYP2C19 (0.46) | CYP2C19SLC6A4SLC6A3SMN1; SMN2HIF1A | |
| SCHEMBL3200007 | 0.74 | CYP2C19 (0.50) | CYP2C19SLC6A4SLC6A3SMN1; SMN2HIF1A | |
| SCHEMBL3190448 | 0.74 | SIGMAR1 (0.47) | CYP2C19SLC6A4SLC6A3SMN1; SMN2HIF1A | |
| SCHEMBL297345 | 0.74 | CYP2C19 (0.46) | CYP2C19SLC6A4SLC6A3SMN1; SMN2HIF1A | |
| SCHEMBL957143 | 0.72 | CYP2C19 (0.44) | CYP2C19SLC6A4SLC6A3SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767322-B2 | Triazolopyridinyl compounds as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767322-B2 | Triazolopyridinyl compounds as kinase inhibitors | RIPK1, RIPK3, RIPK4 | CYP2C19 1596/4885SLC6A4 4259/4885SLC6A3 3648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.