Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165336 | 0.86 | ALDH1A1 (0.39) | ALDH1A1KMT2APOLBMAPTHTT | |
| SCHEMBL17337458 | 0.80 | APEX1 (0.52) | ALDH1A1KMT2AHTTLMNASLC15A2 | |
| SCHEMBL12916982 | 0.78 | ALDH1A1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL21423959 | 0.78 | LMNA (0.44) | POLBLMNA | |
| SCHEMBL28794307 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL25380148 | 0.78 | APEX1 (0.50) | ALDH1A1KMT2AHTTLMNASLC15A2 | |
| SCHEMBL20207765 | 0.75 | ALDH1A1 (0.38) | ALDH1A1KMT2APOLBMAPTHTT | |
| SCHEMBL19919844 | 0.75 | — | — | |
| SCHEMBL4922033 | 0.74 | — | — | |
| SCHEMBL10154890 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330189-A1 | ACYLATED GLP-1 DERIVATIVE | Sciwind Biosciences Co., Ltd. (CN) | 2023-10-19 | — | — | US | disclosed |
| US-20230295260-A1 | GLP RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-09-21 | — | — | US | disclosed |
| US-20180057505-A1 | BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY | VERTEX PHARMACEUTICALS INCORPORATED | 2018-03-01 | — | — | US | disclosed |
| US-8835379-B2 | Derivatives of CGRP | NOVO NORDISK A/S (DK) | 2014-09-16 | — | — | US | disclosed |
| US-8129343-B2 | Acylated GLP-1 compounds | NOVO NORDISK A/S (DK) | 2012-03-06 | — | — | US | disclosed |
| US-20090318353-A1 | Acylated Exendin-4 Compounds | NOVO NORDISK A/S (DK) | 2009-12-24 | — | — | US | disclosed |
| US-20090156478-A1 | Acylated GLP-1 Compounds | NOVO NORDISK A/S (DK) | 2009-06-18 | — | — | US | disclosed |
| US-20080207507-A1 | Extended Glp-1 Compounds | NOVO NORDISK A/S (DK) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207507-A1 | Extended Glp-1 Compounds | GLP1R, GIPR, IAPP | ALDH1A1 2715/4885KMT2A 4148/4885POLB 4624/4885 |
| US-20090318353-A1 | Acylated Exendin-4 Compounds | GLP1R, VIP, IAPP | ALDH1A1 4133/4885KMT2A 1938/4885POLB 4864/4885 |
| US-20090156478-A1 | Acylated GLP-1 Compounds | GLP1R, GIPR, GCGR | ALDH1A1 1380/4885KMT2A 2972/4885POLB 4766/4885 |
| US-20180057505-A1 | BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY | F2RL1, PARP12, TFPI2 | ALDH1A1 3037/4885KMT2A 3714/4885POLB 3450/4885 |
| US-20230295260-A1 | GLP RECEPTOR AGONISTS | GLP1R, GIPR, NPY4R | ALDH1A1 4025/4885KMT2A 2739/4885POLB 4831/4885 |
| US-20230330189-A1 | ACYLATED GLP-1 DERIVATIVE | GLP1R, GIPR, IAPP | ALDH1A1 1909/4885KMT2A 2050/4885POLB 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.