Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 12/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157101 | 0.82 | CDK4 (0.34) | HTTGHSRCDK4CCND1ALDH1A1 | |
| SCHEMBL21336837 | 0.79 | HTT (0.42) | HTTHTR6GHSRALDH1A1 | |
| SCHEMBL24123782 | 0.76 | HTT (0.40) | HTTHTR6L3MBTL1GHSRFLT3 | |
| SCHEMBL10126807 | 0.76 | MAPT (0.56) | HTTHTR6L3MBTL1GHSRFLT3 | |
| SCHEMBL8737585 | 0.75 | HTR3A (0.56) | HTR6ALDH1A1ALDH1A3 | |
| SCHEMBL23328642 | 0.74 | HTT (0.39) | HTTHTR6L3MBTL1GHSRFLT3 | |
| SCHEMBL10126809 | 0.74 | HTT (0.69) | HTTL3MBTL1ALDH1A1 | |
| SCHEMBL16585816 | 0.72 | ADRB1 (0.52) | HTTGHSRALDH1A1 | |
| SCHEMBL18043600 | 0.72 | ADRB1 (0.52) | HTTGHSRALDH1A1 | |
| SCHEMBL10156558 | 0.71 | PIM1 (0.40) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | HTT 3739/4885HTR6 4042/4885L3MBTL1 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.