Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.32 |
| ▸ | AR | P10275 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10126831 | 0.80 | GLA (0.40) | PDE3BPDE3AHSD11B1ALDH1A1HTT | |
| SCHEMBL28239107 | 0.69 | NCF1 (0.45) | ALDH1A1 | |
| SCHEMBL12367734 | 0.67 | NOTUM (0.40) | PDE3BPDE3AKMT2AALDH1A1 | |
| SCHEMBL26418054 | 0.64 | NPSR1 (0.38) | KMT2AALDH1A1HTT | |
| SCHEMBL1399756 | 0.64 | ALDH1A1 (0.40) | KMT2AALDH1A1HTT | |
| SCHEMBL12424154 | 0.64 | ALDH1A1 (0.40) | KMT2AALDH1A1HTT | |
| SCHEMBL25675665 | 0.64 | TRPV1 (0.34) | HSD11B1ALDH1A1TRPV1 | |
| SCHEMBL28239089 | 0.64 | PHGDH (0.40) | HSD11B1HTTTRPV1 | |
| SCHEMBL9640565 | 0.63 | TSHR (0.48) | PDE3BPDE3AKMT2AALDH1A1 | |
| SCHEMBL12424151 | 0.62 | ALDH1A1 (0.48) | KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | CDK4 89/4885CCND1 2436/4885PDE3B 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.