Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256874 | 0.81 | AR (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL12367734 | 0.79 | NOTUM (0.40) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL14256899 | 0.79 | HTR3E (0.61) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL28241543 | 0.79 | GLA (0.32) | TSHRGLAPOLBGAAKMT2A | |
| SCHEMBL7177146 | 0.78 | MAPK1 (0.46) | TSHRGLAPOLBGAAHTR3E | |
| SCHEMBL28155357 | 0.76 | SIRT2 (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL28210229 | 0.76 | CES2 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8248239 | 0.75 | HTR3E (0.43) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10208080 | 0.75 | HSD17B1 (0.36) | GAAHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL19073460 | 0.75 | IDO1 (0.34) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499603-A1 | PHENYLATED POLYIMIDES PREPARED FROM 3,6-DIARYLPYROMELLITIC DIANHYDRIDE AND AROMATIC DIAMINES | THE UNIVERSITY OF AKRON (US) | 1992-08-26 | — | — | EP | claimed |
| WO-1990010025-A1 | PHENYLATED POLYIMIDES PREPARED FROM 3,6-DIARYLPYROMELLITIC DIANHYDRIDE AND AROMATIC DIAMINES | THE UNIVERSITY OF AKRON (US) | 1990-09-07 | — | — | WO | claimed |