Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10156714 | 0.86 | ALDH1A1 (0.60) | MCOLN3TSHRALDH1A1GAANPBWR1 | |
| SCHEMBL10155932 | 0.80 | MCOLN3 (0.72) | MCOLN3TSHRALDH1A1GAANPBWR1 | |
| SCHEMBL281571 | 0.76 | MCOLN3 (0.65) | MCOLN3TSHRALDH1A1GAANPBWR1 | |
| SCHEMBL29944324 | 0.72 | KMT2A (0.74) | TSHRALDH1A1GAANPBWR1KDM4E | |
| SCHEMBL10570472 | 0.72 | TSHR (0.89) | MCOLN3TSHRALDH1A1GAANPBWR1 | |
| SCHEMBL10156466 | 0.72 | L3MBTL1 (0.51) | GAALMNAL3MBTL1 | |
| SCHEMBL29575490 | 0.71 | GAA (0.97) | MCOLN3TSHRALDH1A1GAANPBWR1 | |
| SCHEMBL17008468 | 0.71 | TSHR (0.74) | MCOLN3TSHRALDH1A1GAANPBWR1 | |
| SCHEMBL29736855 | 0.71 | TSHR (0.74) | MCOLN3TSHRALDH1A1GAANPBWR1 | |
| SCHEMBL4468528 | 0.71 | TSHR (0.67) | MCOLN3TSHRALDH1A1GAANPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | MCOLN3 2528/4885TSHR 3964/4885ALDH1A1 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.