Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157896 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HTT | |
| SCHEMBL13685884 | 0.81 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL10568506 | 0.79 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL7759159 | 0.77 | — | — | |
| SCHEMBL2015730 | 0.72 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL9803543 | 0.72 | ALDH1A1 (0.62) | ALDH1A1 | |
| SCHEMBL2220993 | 0.72 | ALDH1A1 (0.62) | ALDH1A1 | |
| SCHEMBL2010219 | 0.71 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL4737789 | 0.71 | ALDH1A1 (0.48) | ALDH1A1 | |
| Silver SCHEMBL2232380 | 0.71 | ALDH1A1 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119806-B2 | Cicletanine derivatives | MERCK SHARP & DOHME CORP. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100029678-A1 | DIURETICS | MERCK SHARP & DOHME CORP. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029678-A1 | DIURETICS | NR3C2, REN, NR3C1 | ALDH1A1 2059/4885HTT 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.