Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 4/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28999248 | 0.97 | ALDH1A1 (0.37) | DNM1MAPTALDH1A1TDP1LMNA | |
| SCHEMBL3241633 | 0.95 | MAPT (0.45) | DNM1MAPTALDH1A1LMNAOPRM1 | |
| SCHEMBL14230548 | 0.95 | MAPT (0.45) | DNM1MAPTALDH1A1LMNAOPRM1 | |
| SCHEMBL28999263 | 0.90 | MAPT (0.35) | MAPTLMNA | |
| SCHEMBL28999238 | 0.90 | ALDH1A1 (0.39) | DNM1MAPTALDH1A1TDP1LMNA | |
| SCHEMBL28999204 | 0.87 | MAPT (0.41) | DNM1MAPTLMNAOPRM1TSHR | |
| SCHEMBL28999207 | 0.87 | MAPT (0.32) | MAPT | |
| SCHEMBL18067441 | 0.87 | DNM1 (0.52) | DNM1MAPTLMNACA2OPRM1 | |
| SCHEMBL8624569 | 0.87 | DNM1 (0.52) | DNM1MAPTLMNACA2OPRM1 | |
| SCHEMBL18394719 | 0.87 | DNM1 (0.52) | DNM1MAPTLMNACA2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140271489-A1 | POLYMERIC DEPOTS FOR LOCALIZATION OF AGENT TO BIOLOGICAL SITES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140271489-A1 | POLYMERIC DEPOTS FOR LOCALIZATION OF AGENT TO BIOLOGICAL SITES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2014-09-18 | — | — | US | disclosed |
| US-20130195954-A1 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130195954-A1 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2013-08-01 | — | — | US | disclosed |
| US-8338492-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338492-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8334324-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-12-18 | — | — | US | disclosed |
| US-8334324-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-12-18 | — | — | US | disclosed |
| US-20120107365-A1 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
| US-20120107365-A1 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
| US-20110152305-A1 | FILMS AND PARTICLES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-20110152305-A1 | FILMS AND PARTICLES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-7671095-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2010-03-02 | — | — | US | disclosed |
| US-7671095-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080075718-A1 | Films and Particles | THE TRUSTEES OF THE BOSTON UNIVERSITY | 2008-03-27 | — | — | US | disclosed |
| US-20080075718-A1 | Films and Particles | THE TRUSTEES OF THE BOSTON UNIVERSITY | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152305-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | DNM1 827/4885MAPT 246/4885ALDH1A1 2505/4885 |
| US-20130195954-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | DNM1 827/4885MAPT 246/4885ALDH1A1 2505/4885 |
| US-20080075718-A1 | Films and Particles | APOB, PGF, ACTB | DNM1 827/4885MAPT 246/4885ALDH1A1 2505/4885 |
| US-20140271489-A1 | POLYMERIC DEPOTS FOR LOCALIZATION OF AGENT TO BIOLOGICAL SITES | CD68, LPXN, CXCL12 | DNM1 1235/4885MAPT 2795/4885ALDH1A1 3186/4885 |
| US-20120107365-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | DNM1 827/4885MAPT 246/4885ALDH1A1 2505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.