SCHEMBL4120188

SCHEMBL4120188

NCCC(CO)S(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
SLC6A6 P31641 1/20 0.36
CYP2C19 P33261 1/20 0.36
BLM P54132 1/20 0.36
APP P05067 1/20 0.33
GABRR1 P24046 2/20 0.31
TP53 P04637 1/20 0.31
GABBR2 O75899 1/20 0.30
GABBR1 Q9UBS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28592838 0.87 BLM (0.41) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL28606533 0.86 APP (0.41) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL28914373 0.84 LMNA (0.39) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL1015907 0.83 LMNA (0.35) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL1638487 0.82 LMNA (0.38) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL4078147 0.81
SCHEMBL8105490 0.81 APP (0.36) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL4895410 0.80 LMNA (0.36) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL271680 0.79 THRB (0.35) TP53
SCHEMBL354817 0.78 LMNA (0.35) LMNASLC6A6CYP2C19BLMAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112255395-A Method for eliminating chyle interference in lipemic sample, immunoturbidimetry kit and application 中生北控生物科技股份有限公司 2021-01-22 CN claimed
CN-105002263-B A kind of reduced coenzyme complex reagent and its application 中生北控生物科技股份有限公司 2018-02-16 CN claimed
CN-112255395-B Method for eliminating chyle interference in lipemic sample, immunoturbidimetry kit and application 中生北控生物科技股份有限公司 2021-06-18 CN disclosed
CN-112255395-A Method for eliminating chyle interference in lipemic sample, immunoturbidimetry kit and application 中生北控生物科技股份有限公司 2021-01-22 CN disclosed
CN-109153791-A The polymer beads of aqueous polymer dispersions modified method, aqueous polymer dispersions, polymer powders redispersible as obtained by the method and the composition comprising the polymer powders redispersible 巴斯夫欧洲公司 2019-01-04 CN disclosed
CN-105002263-B A kind of reduced coenzyme complex reagent and its application 中生北控生物科技股份有限公司 2018-02-16 CN disclosed
CN-105039495-B A kind of 3 α HSD reagents and its preparation method and application 中生北控生物科技股份有限公司 2017-12-15 CN disclosed
CN-105002264-B A kind of tolal bile acid determination reagent box 中生北控生物科技股份有限公司 2017-12-15 CN disclosed
US-9395330-B2 Degradable polyacrylamide gel CASE WESTERN RESERVE UNIVERSITY (US) 2016-07-19 US disclosed
US-20090145758-A1 DEGRADABLE POLYACRYLAMIDE GEL CASE WESTERN RESERVE UNIVERSITY 2009-06-11 US disclosed
EP-1317539-A2 DIRECTED EVOLUTION METHOD MEDICAL RESEARCH COUNCIL (GB) 2003-06-11 EP disclosed
WO-2002022869-A2 DIRECTED EVOLUTION METHOD MEDICAL RESEARCH COUNCIL (GB) 2002-03-21 WO disclosed
EP-0279069-B1 Method and device for ketone measurement ABBOTT LAB (US) 1994-07-13 EP disclosed
US-5174959-A Medical diagnosis; detection of ketones, aldehydes ABBOTT LABORATORIES (US) 1992-12-29 US disclosed
US-5071769-A Quantitative anlaysis of urine and breath sample, monitoring effect of diet ABBOTT LABORATORIES (US) 1991-12-10 US disclosed
US-4970172-A Method and device for ketone measurements ABBOTT LABORATORIES (US) 1990-11-13 US disclosed
EP-0279069-A2 Method and device for ketone measurement ABBOTT LABORATORIES (US) 1988-08-24 EP disclosed
US-4440724-A NITROPRUSSIDE, METAL SALT, TRIS, TAPS HELENA LABORATORIES CORPORATION (US) 1984-04-03 US disclosed