SCHEMBL10159239

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18250148	0.93	KMT2A (0.39)	KMT2AHSP90B1TRAP1FDPSMDH2
	SCHEMBL10159321	0.84	MEN1 (0.37)	KMT2ATRAP1MAPTPOLBMEN1
	SCHEMBL10159337	0.82	KMT2A (0.45)	KMT2ASIGMAR1MAPTPOLBMEN1
	SCHEMBL10159238	0.82	MAPT (0.36)	KMT2AMAPTPOLBMEN1USP2
	SCHEMBL10159457	0.81	MEN1 (0.34)	KMT2AMAPTPOLBMEN1USP2
	SCHEMBL10159274	0.80	MAPT (0.42)	KMT2AMAPTPOLBMEN1USP2
	SCHEMBL18250149	0.78	ALDH1A1 (0.37)	KMT2AMAPTPOLBMEN1SMN1; SMN2
	SCHEMBL10195157	0.78	TRAP1 (0.42)	KMT2ATRAP1MAPTPOLBMEN1
	SCHEMBL10159199	0.78	TRAP1 (0.39)	KMT2AHSP90B1TRAP1MDH2MAPT
	SCHEMBL18250150	0.78	KMT2A (0.37)	KMT2AMDH2MAPTPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.