SCHEMBL10159337

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18250152	0.93	ALDH1A1 (0.41)	KMT2AMEN1CASP6ATMMAPT
	SCHEMBL10159457	0.86	MEN1 (0.34)	KMT2AMEN1CASP6MAPTUSP2
	SCHEMBL10159335	0.85	MEN1 (0.41)	KMT2AMEN1MAPTUSP2GAA
	SCHEMBL10159321	0.83	MEN1 (0.37)	KMT2AMEN1MAPTUSP2GAA
	SCHEMBL10158936	0.83	KMT2A (0.54)	KMT2AMEN1MAPTUSP2GAA
	SCHEMBL10159239	0.82	KMT2A (0.43)	KMT2AMEN1MAPTUSP2GAA
	SCHEMBL10159240	0.81	METAP2 (0.33)	KMT2AMEN1MAPTUSP2GAA
	SCHEMBL10159238	0.81	MAPT (0.36)	KMT2AMEN1MAPTUSP2GAA
	SCHEMBL18250145	0.79	NR3C1 (0.32)	KMT2AMEN1MAPTUSP2GAA
	SCHEMBL10159193	0.79	KMT2A (0.39)	KMT2AMEN1CASP6ATMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.