Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TYMP | P19971 | 5/20 | 0.45 |
| ▸ | TK1 | P04183 | 3/20 | 0.45 |
| ▸ | TK2 | O00142 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26269249 | 0.84 | ALDH1A1 (0.49) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL26268069 | 0.84 | ALDH1A1 (0.49) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL14534560 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL16473366 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL15085979 | 0.80 | TK2 (0.43) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL11981098 | 0.80 | TK2 (0.43) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL13615532 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL10159455 | 0.80 | SLC28A1 (0.46) | — | |
| SCHEMBL10159533 | 0.80 | SLC28A1 (0.46) | — | |
| SCHEMBL25966287 | 0.80 | SLC28A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927513-B2 | 5′ phosphate mimics | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20120157511-A1 | 5' PHOSPHATE MIMICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157511-A1 | 5' PHOSPHATE MIMICS | NSUN2, RNGTT, RNMT | ALDH1A1 3422/4885LMNA 2073/4885ALB 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.