Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TK1 | P04183 | 4/20 | 0.44 |
| ▸ | TK2 | O00142 | 2/20 | 0.41 |
| ▸ | TYMP | P19971 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616344 | 0.81 | SLC28A1 (0.46) | — | |
| SCHEMBL10159604 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL16473393 | 0.80 | TK1 (0.43) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL13615609 | 0.79 | TK1 (0.36) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL16473410 | 0.76 | TK1 (0.38) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL16473373 | 0.76 | TK1 (0.38) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL16473421 | 0.76 | LMNA (0.44) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL16473381 | 0.76 | LMNA (0.44) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL16473416 | 0.74 | TK1 (0.43) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL16473402 | 0.73 | TK1 (0.37) | ALDH1A1LMNAALBPOLBADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143369-A2 | METHOD OF PREPARING NUCLEOSIDES AND ANALOGS THEREOF WITHOUT USING CHROMATOGRAPHY | ISIS PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |