Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.37 |
| ▸ | TUBB | P07437 | 3/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13283977 | 0.98 | HTT (0.40) | HTTCYP1A2CYP2D6HPGDCYP2C19 | |
| SCHEMBL10132737 | 0.92 | HTT (0.38) | HTTCYP1A2CYP2D6HPGDCYP2C19 | |
| SCHEMBL10163166 | 0.84 | TUBB4A (0.42) | HTTCYP1A2CYP2D6HPGDCYP2C19 | |
| SCHEMBL10132857 | 0.82 | NPSR1 (0.38) | HTTACHENPSR1LMNAALDH1A1 | |
| SCHEMBL10163248 | 0.82 | TUBB4A (0.41) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10161868 | 0.81 | ALDH1A1 (0.40) | HTTCYP1A2CYP2D6HPGDCYP2C19 | |
| SCHEMBL419335 | 0.80 | NPSR1 (0.38) | HTTCYP1A2HPGDNPSR1LMNA | |
| SCHEMBL10162955 | 0.78 | PDE3B (0.39) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10162989 | 0.78 | LMNA (0.47) | HTTNPSR1LMNAALDH1A1KMT2A | |
| SCHEMBL10161750 | 0.77 | TUBB4A (0.43) | HTTHPGDTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | HTT 4360/4885CYP1A2 127/4885CYP2D6 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.