SCHEMBL10165698

SCHEMBL10165698

c1ccc2cc(-n3c4ccccc4c4cc(-c5cccc6c5sc5ccccc56)ccc43)ccc2c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.49
PRKDC P78527 5/20 0.38
PMM2 O15305 1/20 0.36
MPI P34949 1/20 0.36
PHOSPHO1 Q8TCT1 1/20 0.36
S1PR5 Q9H228 11/20 0.36
S1PR4 O95977 8/20 0.36
PARP14 Q460N5 1/20 0.34
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
BRD4 O60885 1/20 0.32
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32
PIK3CG P48736 1/20 0.32
KCNH2 Q12809 1/20 0.32
BRDT Q58F21 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL780874 0.97 ALOX5 (0.48) ALOX5PRKDCPMM2MPIPHOSPHO1
SCHEMBL15630630 0.97 ALOX5 (0.50) ALOX5PRKDCPMM2MPIPHOSPHO1
SCHEMBL22672322 0.96 ALOX5 (0.46) ALOX5PRKDCPMM2MPIPHOSPHO1
SCHEMBL18779549 0.96 ALOX5 (0.46) ALOX5PRKDCPMM2MPIPHOSPHO1
SCHEMBL18779514 0.96 ALOX5 (0.46) ALOX5PRKDCPMM2MPIPHOSPHO1
SCHEMBL24303780 0.96 ALOX5 (0.44) ALOX5PRKDCPMM2MPIPHOSPHO1
SCHEMBL10165741 0.96 ALOX5 (0.44) ALOX5PRKDCPMM2MPIPHOSPHO1
SCHEMBL18804959 0.95 ALOX5 (0.45) ALOX5PRKDCPMM2MPIPHOSPHO1
SCHEMBL18804975 0.95 ALOX5 (0.45) ALOX5PRKDCPMM2MPIPHOSPHO1
SCHEMBL18623556 0.94 ALOX5 (0.44) ALOX5PRKDCPMM2MPIPHOSPHO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210351358-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-11-11 US disclosed
US-11165024-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-02 US disclosed
US-20200235303-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-23 US disclosed
US-10014480-B2 Heterocyclic compounds and organic electroluminescent devices using the same E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2018-07-03 US disclosed
US-10014480-B2 Heterocyclic compounds and organic electroluminescent devices using the same E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2018-07-03 US disclosed
US-20170256722-A1 A HOLE TRANSPORT MATERIAL AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-09-07 US disclosed
US-20170256722-A1 A HOLE TRANSPORT MATERIAL AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-09-07 US disclosed
US-20170244043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-24 US disclosed
US-20170244043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-24 US disclosed
US-20160133848-A1 HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME E-RAY OPTOELECTRONICS TECHONOLOGY CO., LTD. (TW) 2016-05-12 US disclosed
US-20160133848-A1 HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME E-RAY OPTOELECTRONICS TECHONOLOGY CO., LTD. (TW) 2016-05-12 US disclosed
WO-2016036207-A1 A HOLE TRANSPORT MATERIAL AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-03-10 WO disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170256722-A1 A HOLE TRANSPORT MATERIAL AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME HTT, VDAC1, VAPA ALOX5 1815/4885PRKDC 4354/4885PMM2 3661/4885
US-20160133848-A1 HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LEF1, HVCN1, KCNC1 ALOX5 1064/4885PRKDC 4516/4885PMM2 4204/4885
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element NUTF2, BRI3BP, CLINT1 ALOX5 1931/4885PRKDC 2968/4885PMM2 4836/4885
US-10014480-B2 Heterocyclic compounds and organic electroluminescent devices using the same LEF1, HVCN1, KCNC1 ALOX5 1064/4885PRKDC 4516/4885PMM2 4204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.