Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101821 | 0.83 | ALDH1A1 (0.53) | PTGS1LMNAALDH1A1TSHRPOLB | |
| SCHEMBL102698 | 0.76 | PTGS1 (0.53) | PTGS1ALDH1A1TSHRPOLBLTA4H | |
| SCHEMBL7429283 | 0.73 | NPC1 (0.59) | ALDH1A1MEN1KMT2A | |
| SCHEMBL511341 | 0.72 | ALDH1A1 (0.57) | LMNAALDH1A1POLBBCL9CTNNB1 | |
| SCHEMBL6481775 | 0.70 | ALDH1A1 (0.56) | PTGS1LMNAALDH1A1HPGDMEN1 | |
| SCHEMBL17253651 | 0.70 | CYP3A4 (0.53) | PTGS1ALDH1A1TSHR | |
| SCHEMBL102366 | 0.70 | PTGS1 (0.54) | PTGS1ALDH1A1TSHRLTA4HNR3C1 | |
| SCHEMBL102353 | 0.70 | MEN1 (0.63) | PTGS1ALDH1A1POLBHPGDMEN1 | |
| SCHEMBL5133639 | 0.69 | PTGS1 (0.68) | PTGS1LMNAALDH1A1TSHRLTA4H | |
| SCHEMBL101653 | 0.69 | PTGS1 (0.68) | PTGS1ALDH1A1TSHRPOLBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343971-B2 | Pharmacologically-active vanilloid carbamates | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-01-01 | — | — | US | disclosed |
| US-20120059007-A1 | Pharmacologically-active vanilloid carbamates | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059007-A1 | Pharmacologically-active vanilloid carbamates | FAAH, FAAH2, TRPV1 | PTGS1 74/4885LMNA 4344/4885ALDH1A1 2053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.