SCHEMBL10167544

SCHEMBL10167544

CS(C)=Nc1nsc2cccc(OC(F)F)c12

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10167693 0.83 KCNA5 (0.42) KCNA5
SCHEMBL3991335 0.74 ALDH1A1 (0.34) KCNA5
SCHEMBL12292166 0.73 KCNA5 (0.41) KCNA5
SCHEMBL12292170 0.71 KCNA5 (0.40) KCNA5
SCHEMBL13903694 0.70 KDM4E (0.34) KCNA5
SCHEMBL289236 0.70 KCNA5 (0.47) KCNA5
SCHEMBL2238634 0.69 HCRTR1 (0.36) KCNA5
SCHEMBL289237 0.69 KCNA5 (0.30) KCNA5
SCHEMBL10167481 0.68 HCRTR1 (0.34)
SCHEMBL10167485 0.65 HCRTR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119568-B2 3-amino-1,2-benzisothiazole compounds for combating animal pest II BASF SE (DE) 2012-02-21 US disclosed
US-8119568-B2 3-amino-1,2-benzisothiazole compounds for combating animal pest II BASF SE (DE) 2012-02-21 US disclosed
US-20100009848-A1 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II BASF SE (DE) 2010-01-14 US disclosed
US-20100009848-A1 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II BASF SE (DE) 2010-01-14 US disclosed
WO-2008090048-A2 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II BASF SE (DE) 2008-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100009848-A1 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II BPNT1, BCAT1, TGFBR1 KCNA5 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.