Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 13/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10167648 | 0.89 | MAPT (0.59) | MAPTGPBAR1MEN1KMT2A | |
| SCHEMBL10167652 | 0.83 | MAPT (0.46) | MAPTGPBAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10167617 | 0.80 | SCN9A (0.41) | MAPTSCN5ASCN9AALDH1A1 | |
| SCHEMBL10167485 | 0.80 | HCRTR1 (0.33) | MAPTHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL10167491 | 0.79 | LMNA (0.40) | MAPTMEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL10167582 | 0.79 | MAPT (0.56) | MAPTGPBAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10167481 | 0.78 | HCRTR1 (0.34) | MAPTKMT2AHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL10167484 | 0.75 | HCRTR1 (0.35) | MAPTMEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL10167555 | 0.75 | KCNQ3 (0.36) | SCN9AMEN1KMT2AALDH1A1 | |
| SCHEMBL351412 | 0.74 | PDE4A (0.34) | MAPTMEN1KMT2AHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| WO-2008090048-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BPNT1, BCAT1, TGFBR1 | MAPT 2569/4885GPBAR1 313/4885SCN5A 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.