Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 8/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 8/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10167578 | 0.88 | L3MBTL1 (0.42) | KCNQ3KCNQ2GRM4POLBPKM | |
| SCHEMBL10167556 | 0.88 | KMT2A (0.35) | KCNQ3KCNQ2GRM4POLBPKM | |
| SCHEMBL10167491 | 0.84 | LMNA (0.40) | ALDH1A1KMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL351633 | 0.83 | KMT2A (0.40) | KCNQ3KCNQ2POLBPKML3MBTL1 | |
| SCHEMBL353442 | 0.82 | LMNA (0.36) | GRM4POLBPKML3MBTL1NAPRT | |
| SCHEMBL10167594 | 0.80 | KCNQ3 (0.44) | KCNQ3KCNQ2POLBKCNE1KCNQ1 | |
| SCHEMBL10167481 | 0.80 | HCRTR1 (0.34) | POLBL3MBTL1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10167484 | 0.77 | HCRTR1 (0.35) | POLBALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10167485 | 0.77 | HCRTR1 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10167584 | 0.75 | L3MBTL1 (0.42) | KCNQ3KCNQ2GRM4POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| WO-2008090048-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BPNT1, BCAT1, TGFBR1 | KCNQ3 952/4885KCNQ2 853/4885GRM4 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.