SCHEMBL101687

SCHEMBL101687

O=C(Cl)c1ccc(C(=O)Cl)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
CASP1 P29466 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SRD5A2 P31213 2/20 0.43
MAPT P10636 3/20 0.42
KDM4E B2RXH2 2/20 0.42
RAB9A P51151 3/20 0.40
ALDH1A1 P00352 4/20 0.39
MAPK1 P28482 1/20 0.39
HIF1A Q16665 1/20 0.39
KMO O15229 2/20 0.38
NPC1 O15118 2/20 0.38
HPGD P15428 2/20 0.38
CASP3 P42574 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 1/20 0.37
PKM P14618 1/20 0.37
KMT2A Q03164 1/20 0.37
TTR P02766 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11806931 0.98 TSHR (0.43) TSHRCASP1SMN1; SMN2SRD5A2MAPT
SCHEMBL9618406 0.82 TSHR (0.45) TSHRSRD5A2MAPTKDM4ERAB9A
SCHEMBL75886 0.81 ALDH1A1 (0.40) TSHRCASP1SMN1; SMN2SRD5A2MAPT
SCHEMBL110094 0.81 TSHR (0.67) TSHRSRD5A2MAPTKDM4ERAB9A
SCHEMBL29440655 0.81 ALDH1A1 (0.40) TSHRCASP1SMN1; SMN2SRD5A2MAPT
SCHEMBL29514652 0.81 TSHR (0.67) TSHRSRD5A2MAPTKDM4ERAB9A
SCHEMBL6243384 0.81 KDM4E (0.50) CASP1SMN1; SMN2MAPTKDM4ERAB9A
SCHEMBL6238741 0.81 ALDH1A1 (0.54) TSHRCASP1SMN1; SMN2MAPTKDM4E
SCHEMBL27483787 0.81 ATM (0.53) SRD5A2KDM4ERAB9AALDH1A1NPC1
SCHEMBL4429793 0.79 POLB (0.44) TSHRSMN1; SMN2MAPTRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 611 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109942810-B Aromatic heterocyclic polyamide composite film with high breakdown strength and preparation method thereof 四川大学 2021-07-23 CN claimed
US-9790622-B2 Copolymer fibers and yarns and processes for making same E I DU PONT DE NEMOURS AND COMPANY (US) 2017-10-17 US claimed
US-20170016145-A1 COPOLYMER FIBERS AND YARNS AND PROCESSES FOR MAKING SAME DUPONT SAFETY & CONSTRUCTION, INC. 2017-01-19 US claimed
US-9481946-B2 Copolymer fibers and yarns and processes for making same E I DU PONT DE NEMOURS AND COMPANY (US) 2016-11-01 US claimed
EP-2663676-B1 COPOLYMER FIBERS AND YARNS AND PROCESSES FOR MAKING SAME DU PONT (US) 2015-12-16 EP claimed
EP-2663676-A1 COPOLYMER FIBERS AND YARNS AND PROCESSES FOR MAKING SAME E.I. Du Pont De Nemours And Company (US) 2013-11-20 EP claimed
US-20130075950-A1 COPOLYMER FIBERS AND YARNS AND PROCESSES FOR MAKING SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-03-28 US claimed
WO-2012097228-A1 COPOLYMER FIBERS AND YARNS AND PROCESSES FOR MAKING SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-19 WO claimed
EP-2094890-B1 METHOD FOR OBTAINING HIGH-TENACITY ARAMID YARN TEIJIN ARAMID BV (NL) 2010-01-20 EP claimed
EP-0572002-B1 Para-aramide dope of low degree of polymerization, para-aramide fiber and para-aramide pulp produced therefrom and processes for producing the same SUMITOMO CHEMICAL CO (JP) 2000-08-30 EP claimed
EP-0344594-A1 Thermoplastic aromatic copolyetheramide, process for its preparation and its use to produce molded articles HOECHST AKTIENGESELLSCHAFT (DE) 1989-12-06 EP claimed
EP-0344593-A1 Process for the preparation of molded articles of a thermoplastic aromatic polyetheramide HOECHST AKTIENGESELLSCHAFT (DE) 1989-12-06 EP claimed
EP-0028353-B2 PROCESS FOR PRODUCING AN AROMATIC POLYESTERPOLYCARBONATE MITSUBISHI KASEI CORPORATION (JP) 1987-12-23 EP claimed
EP-0028353-B1 PROCESS FOR PRODUCING AN AROMATIC POLYESTERPOLYCARBONATE MITSUBISHI KASEI CORPORATION (JP) 1983-09-07 EP claimed
US-4395534-A Process for producing aromatic polyester carbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-07-26 US claimed
EP-0008492-B1 METHOD FOR MANUFACTURE OF AROMATIC POLYESTER-POLYCARBONATE MITSUBISHI KASEI CORPORATION (JP) 1983-05-18 EP claimed
US-4369303-A Process for producing an aromatic polyesterpolycarbonate MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-01-18 US claimed
EP-0028353-A1 Process for producing an aromatic polyesterpolycarbonate MITSUBISHI KASEI CORPORATION (JP) 1981-05-13 EP claimed
US-4252939-A Method for manufacture of aromatic polyester-polycarbonate MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1981-02-24 US claimed
EP-0008492-A1 Method for manufacture of aromatic polyester-polycarbonate MITSUBISHI KASEI CORPORATION (JP) 1980-03-05 EP claimed