SCHEMBL75886

SCHEMBL75886

O=C(Cl)c1ccc(C(=O)Cl)c(C(=O)Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
TSHR P16473 5/20 0.39
ALOX15 P16050 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38
KDM4E B2RXH2 4/20 0.36
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
SRD5A2 P31213 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 2/20 0.32
CASP1 P29466 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAOB P27338 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29440655 1.00 ALDH1A1 (0.40) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL8306753 0.89 CDC25B (0.52) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL11704191 0.89 HSD17B10 (0.52) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL338194 0.88 TDP1 (0.48) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL6560811 0.86 KDM4E (0.52) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL15561292 0.83 MAPT (0.50) ALDH1A1KDM4EPOLBTDP1L3MBTL1
SCHEMBL13139835 0.83 CYP2C8 (0.39) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL8309710 0.82 KDM4E (0.51) ALDH1A1TSHRHSD17B10KDM4ETDP1
SCHEMBL11428944 0.82 KDM4E (0.51) ALDH1A1TSHRHSD17B10KDM4ETDP1
SCHEMBL1773780 0.81 CES2 (0.39) ALDH1A1TSHRALOX15HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4140 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117000047-B Oxidation-resistant, antibacterial and high-flux reverse osmosis membrane and preparation method and application thereof 万华化学集团股份有限公司 2026-05-19 CN claimed
US-12616948-B2 Polyamide microcapsules FIRMENICH SA (CH) 2026-05-05 US claimed
CN-120054221-A High-temperature-resistant composite reverse osmosis membrane and preparation method thereof 沃顿科技股份有限公司 2025-05-30 CN claimed
US-20250163265-A1 TRANSPARENT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2025-05-22 US claimed
CN-120020114-A Preparation method of N-alkenyl amide compound 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120020115-A Process for the preparation of N- (alkyl-2-hydroxy) alkylamides and N-alkenylamides 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-119971778-A Preparation method and application of nanoparticle blending modified forward osmosis membrane 宁波大学 2025-05-13 CN claimed
CN-116510764-B Preparation method of micro-filtration/nanofiltration double-layer catalytic membrane based on double-site carbon nitride and in-situ self-Fenton application thereof 苏州科技大学 2025-02-28 CN claimed
EP-3486271-B1 POLYIMIDE-BASED BLOCK COPOLYMER AND POLYIMIDE-BASED FILM COMPRISING SAME LG CHEMICAL LTD (KR) 2025-02-19 EP claimed
EP-3412732-B1 POLYIMIDE-BASED BLOCK COPOLYMER FILM LG CHEMICAL LTD (KR) 2025-02-19 EP claimed
EP-0072002-B1 HIGH PERFORMANCE SEMIPERMEABLE COMPOSITE MEMBRANE AND PROCESS FOR PRODUCING SAME TORAY INDUSTRIES, INC. (JP) 1985-04-10 EP claimed
US-4452966-A REACTING A POLYCARBONATE OLIGOMER WITH A THREE FUNCTIONAL GROUP COMPOUND, THEN A DIHYDRIC PHENOL IDEMITSU KOSAN COMPANY LIMITED (JP) 1984-06-05 US claimed
EP-0093914-A1 Process for the production of polycarbonate IDEMITSU KOSAN COMPANY LIMITED (JP) 1983-11-16 EP claimed
EP-0072002-A1 High performance semipermeable composite membrane and process for producing same TORAY INDUSTRIES, INC. (JP) 1983-02-16 EP claimed
EP-0067695-A1 Process for the preparaton of nylon block polymers DSM RIM NYLON V.O.F (NL) 1982-12-22 EP claimed
EP-0067693-A1 Acid halide and acyllactam functional materials DSM RIM NYLON V.O.F (NL) 1982-12-22 EP claimed
EP-0041551-A4 BLENDS OF POLYETHERIMIDES AND POLYAMIDEIMIDES. GEN ELECTRIC (US) 1982-04-22 EP claimed
EP-0041551-A1 BLENDS OF POLYETHERIMIDES AND POLYAMIDEIMIDES. GEN ELECTRIC (US) 1981-12-16 EP claimed
WO-1981001568-A1 BLENDS OF POLYETHERIMIDES AND POLYAMIDEIMIDES GEN ELECTRIC (US) 1981-06-11 WO claimed
US-4258155-A FOR COATINGS AND MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1981-03-24 US claimed