SCHEMBL29440655

SCHEMBL29440655

O=C(Cl)c1ccc(C(=O)Cl)c(C(=O)Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
TSHR P16473 5/20 0.39
ALOX15 P16050 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38
KDM4E B2RXH2 4/20 0.36
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
SRD5A2 P31213 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 2/20 0.32
CASP1 P29466 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAOB P27338 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75886 1.00 ALDH1A1 (0.40) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL8306753 0.89 CDC25B (0.52) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL11704191 0.89 HSD17B10 (0.52) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL338194 0.88 TDP1 (0.48) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL6560811 0.86 KDM4E (0.52) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL15561292 0.83 MAPT (0.50) ALDH1A1KDM4EPOLBTDP1L3MBTL1
SCHEMBL13139835 0.83 CYP2C8 (0.39) ALDH1A1TSHRALOX15HSD17B10CDC25A
SCHEMBL8309710 0.82 KDM4E (0.51) ALDH1A1TSHRHSD17B10KDM4ETDP1
SCHEMBL11428944 0.82 KDM4E (0.51) ALDH1A1TSHRHSD17B10KDM4ETDP1
SCHEMBL1773780 0.81 CES2 (0.39) ALDH1A1TSHRALOX15HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118949689-A Amphoteric ion modified fluorine-containing poly (ester) amide thin layer composite reverse osmosis membrane, and preparation method and application thereof 天津工业大学绍兴柯桥研究院 2024-11-15 CN claimed
CN-116440328-B Regulation method of degradation period of acellular biological tissue material and application thereof 爱美客技术发展股份有限公司 2024-10-29 CN claimed
CN-118615887-A Fluorine-containing poly (ester) amide thin layer composite reverse osmosis membrane, and preparation method and application thereof 天津工业大学绍兴柯桥研究院 2024-09-10 CN claimed
CN-117024841-A Polyimide and polyarylester interpenetrating network porous material and preparation method thereof 大连中科聚合新材料科技有限公司 2023-11-10 CN claimed
CN-116789955-A Interfacial polymerization method based on polymerizable eutectic solvent and alkane, polyamide membrane and preparation method thereof 山东中康国创先进印染技术研究院有限公司 2023-09-22 CN claimed
CN-116440328-A Regulation method of degradation period of acellular biological tissue material and application thereof 爱美客技术发展股份有限公司 2023-07-18 CN claimed
EP-4196257-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES Firmenich SA (CH) 2023-06-21 EP claimed
EP-4178715-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES Firmenich SA (CH) 2023-05-17 EP claimed
CN-114904399-B Interfacial polymerization method based on eutectic solvent and alkane, polyamide composite membrane and preparation method thereof 山东中康国创先进印染技术研究院有限公司 2023-05-16 CN claimed
WO-2022136008-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES FIRMENICH SA (CH) 2022-06-30 WO claimed
WO-2022136007-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES FIRMENICH SA (CH) 2022-06-30 WO claimed
CN-114130220-A Preparation method of polytriazine alkali-resistant composite nanofiltration membrane 万华化学集团股份有限公司 2022-03-04 CN claimed
EP-4713129-A1 ORGANOSILICON-BASED MICROCAPSULES Firmenich SA (CH) 2026-03-25 EP disclosed
EP-4688246-A1 COACERVATE CORE-SHELL MICROCAPSULES Firmenich SA (CH) 2026-02-11 EP disclosed
EP-4633791-A1 PROTEIN-BASED MICROCAPSULES Firmenich SA (CH) 2025-10-22 EP disclosed
EP-4633790-A1 POLYAMIDE-BASED MICROCAPSULES Firmenich SA (CH) 2025-10-22 EP disclosed
WO-2022171450-A1 HYBRID MICROCAPSULES COMPRISING LIGNIN PARTICLES FIRMENICH SA (CH) 2022-08-18 WO disclosed
WO-2022136008-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES FIRMENICH SA (CH) 2022-06-30 WO disclosed
WO-2022136007-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES FIRMENICH SA (CH) 2022-06-30 WO disclosed
CN-114130220-A Preparation method of polytriazine alkali-resistant composite nanofiltration membrane 万华化学集团股份有限公司 2022-03-04 CN disclosed