Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12649210 | 0.92 | FTO (0.37) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10169409 | 0.92 | FTO (0.46) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL14236668 | 0.79 | FTO (0.38) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL14236566 | 0.76 | POLB (0.40) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL24358396 | 0.75 | FTO (0.46) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL12228681 | 0.75 | SLC6A1 (0.43) | MEN1KMT2ACYP2C19CYP2C9ALOX15 | |
| SCHEMBL418120 | 0.70 | MAPT (0.42) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL3471424 | 0.70 | MAPT (0.44) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL29452872 | 0.70 | FTO (0.50) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL14740590 | 0.70 | FTO (0.50) | FTOMAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534902-B2 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-19 | — | — | US | disclosed |