SCHEMBL10169910

SCHEMBL10169910

c1ccc([PH](CCCOCC[PH](c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
KCNA3 P22001 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NCF1 P14598 3/20 0.32
HRH3 Q9Y5N1 2/20 0.32
LMNA P02545 2/20 0.31
RECQL P46063 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NAAA Q02083 2/20 0.30
HRH4 Q9H3N8 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838146 0.91 TSHR (0.36) TSHRKCNA3MEN1KMT2ASMN1; SMN2
SCHEMBL14790917 0.89 LMNA (0.39) TSHRKCNA3MEN1KMT2ASMN1; SMN2
SCHEMBL19736626 0.86 TSHR (0.45) TSHRRECQLALDH1A1TDP1L3MBTL1
SCHEMBL15128610 0.86 TSHR (0.45) TSHRRECQLALDH1A1TDP1L3MBTL1
SCHEMBL13096691 0.84 CA2 (0.37) TSHRMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL4686266 0.83 TSHR (0.54) TSHRHRH3TDP1L3MBTL1NAAA
Bromide SCHEMBL29284774 0.82 TSHR (0.52) TSHRHRH3TDP1L3MBTL1NAAA
SCHEMBL838143 0.81 TSHR (0.39) TSHRKCNA3ALDH1A1TDP1
SCHEMBL106258 0.81 TSHR (0.39) TSHRKCNA3ALDH1A1TDP1
SCHEMBL9114285 0.81 KCNA3 (0.60) KCNA3RECQLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 US disclosed
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090114108-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-05-07 US disclosed