SCHEMBL838146

SCHEMBL838146

c1ccc([PH](CCOCC[PH](c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
KMT2A Q03164 2/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 1/20 0.35
KCNA3 P22001 1/20 0.35
ALDH1A1 P00352 6/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
PTK2B Q14289 1/20 0.32
NCF1 P14598 3/20 0.32
MAPK1 P28482 2/20 0.31
KDM4E B2RXH2 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
RECQL P46063 1/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14790917 0.97 LMNA (0.39) TSHRKMT2ALMNAMEN1KCNA3
SCHEMBL10169910 0.91 TSHR (0.36) TSHRKMT2ALMNAMEN1KCNA3
SCHEMBL14493580 0.89 ALDH1A1 (0.43) TSHRKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL17467574 0.89 TAAR1 (0.43) TSHRKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL13448099 0.87 CA1 (0.40) TSHRKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL17467576 0.87 TAAR1 (0.42) TSHRKMT2ALMNAMEN1ALDH1A1
SCHEMBL18323388 0.86 NCF1 (0.38) ALDH1A1SMN1; SMN2NCF1KDM4ERAB9A
SCHEMBL19736626 0.85 TSHR (0.45) TSHRALDH1A1TDP1RECQLL3MBTL1
SCHEMBL14128885 0.84 TSHR (0.56) TSHRALDH1A1SMN1; SMN2MAPK1KDM4E
SCHEMBL17467570 0.84 HTR1B (0.48) TSHRKMT2ALMNAMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9032876-B2 Lithographic printing plate precursor, lithographic printing plate platemaking method, and polymerizable monomer FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
EP-2570853-B1 Oxygen-blocking film and lithographic printing plate precursor comprising said film FUJIFILM CORP (JP) 2014-08-20 EP disclosed
US-8426102-B2 Lithographic printing plate precursor and plate making method FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-20130071786-A1 COATING COMPOSITION AND IMAGE-FORMING MATERIAL, LITHOGRAPHIC PRINTING PLATE PRECURSOR AND OXYGEN-BLOCKING FILM INCLUDING THE COATING COMPOSITION FUJIFILM CORPORATION (JP) 2013-03-21 US disclosed
US-20130071786-A1 COATING COMPOSITION AND IMAGE-FORMING MATERIAL, LITHOGRAPHIC PRINTING PLATE PRECURSOR AND OXYGEN-BLOCKING FILM INCLUDING THE COATING COMPOSITION FUJIFILM CORPORATION (JP) 2013-03-21 US disclosed
US-8399172-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2013-03-19 US disclosed
US-8309294-B2 2012-11-13 US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8221957-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
US-8187791-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-20090075208-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-03-19 US disclosed
US-20090047601-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-02-19 US disclosed
US-20080318155-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD FUJIFILM CORPORATION (JP) 2008-12-25 US disclosed
US-20080286685-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080254384-A1 Cyanine dye containing methine chain and onium salt structure FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
US-20080096132-A1 mixing a polymerizable monomer in which acrylonitrile accounts for 70% by weight or more of a total of the polymerizable monomer, water and an alkali metal persulfate polymerization initiator to conduct emulsion polymerization; distilling off unpolymerized monomers; chemical resistance film, gas barrier FUJIFILM CORPORATION 2008-04-24 US disclosed
US-20080087183-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-20070214987-A1 Lithographic printing plate precursor FUJIFILM CORPORATION 2007-09-20 US disclosed
US-20070042293-A1 Including an aromatic diphosphonium compound along with an addition polymerization promoter, unsaturated compound, protective layeron an sluminium support; laser recording having excellent ink receptibility during printing and printing durability; strength; on-press development; image strength FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080254384-A1 Cyanine dye containing methine chain and onium salt structure INMT, MGMT, IK TSHR 3985/4885KMT2A 652/4885LMNA 1493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.